Arrowsmith, the most widely read of Sinclair Lewis's novels, is the incisive portrait of a man passionately devoted to science. As a bright, curious boy in a small Midwestern town, Martin Arrowsmith spends his free time in old Doc Vickerson's office avidly devouring medical texts. Destined to become a physician and a researcher, he discovers that societal forces of ignorance, greed, and corruption can be as life-threatening as the plague.

Part satire, part morality tale, Lewis's Pulitzer Prize-winning novel illuminates the mystery and power of science while giving enduring life to a singular American hero's struggle for integrity and intellectual freedom in a small-minded world.

With an Introduction by Sally E. Parry
and an Afterword by E. L. Doctorow