Marina's relationships have a rocky history, with a controlling mother, distant sister, and a string of lousy boyfriends. In the midst of her troubles, Marina's family discovers her four-year-old nephew, Christopher, is diagnosed with a life-threatening illness. Her mother orders her to go to the Greek island of Santorini to retrieve her great-grandmother's wonder-working icon of Saints Anna and Mary for healing of her nephew. Fearing Christopher's condition and desiring separation from her family, Marina accepts the trip with little deliberation. But when she reaches the island and the church that houses the icon, she finds it's been stolen. Marina recruits a high school English teacher vacationing on the island, to help her search for her great-grandmother's precious heirloom. During the search, she finds more than the icon.