Over the summer, fashion-loving Zoey Webber gets the best news ever: Her middle school is getting rid of uniforms! There's just one problem. Zoey has sketchbooks full of fashion designs, but nothing to wear! So with a little help from her best friends Kate and Priti, she learns to make her own clothes. She even begins to post her fashion design sketches online in a blog. That's how the Sew Zoey blog begins, and soon it becomes much more.

Zoey's quirky style makes her a bit of a misfit at middle school, but her Sew Zoey blog quickly gains a dedicated following. Real fashion designers start to read it! Yet even as her blog takes off, Zoey still has to deal with homework, crushes, and P.E. class. And when the principal asks her to design a dress for the school's fashion-show fund-raiser, Zoey can't wait to start sewing! But what will happen when her two worlds collide?