When a fame-hungry scientist brings an impossible, living specimen of a creature long thought extinct back from the wild jungles of South America he unwittingly brings along a passenger. Something with the potential to destroy every living thing on our planet.

The infestation begins, rapidly overtaking medical resources and resisting all treatment. One woman knows the danger, Carla Nero, chief scientist of the Center for Disease Control. She makes Matt an offer he can't refuse and together they join a team heading to the deep jungle in a desperate race to locate the hidden place where the specimen was taken.

Only by finding the location of the specimen can the team - and the world - hope to uncover the secret of how to survive the ancient, horrifying parasite that has been released.