It's summer 2002 and a mysterious plague has swept across the planet, killing every grown mammal and embryo possessing a Y chromosome--except for one man. For some reason, amateur escape artist Yorick Brown is the only human male to survive the androcide that has wiped out almost half of the global population.

Accompanied by his pet monkey, Ampersand--who is also immune to the pandemic--and aided by his politician mother and the enigmatic Agent 355, Yorick must struggle to survive in a world where he is now the most endangered species.

Y: The Last Man Compendium One collects issues #1-31 of the critically acclaimed series created by the award-winning team of writer BRIAN K. VAUGHAN (Ex Machina, Runaways) and artist PIA GUERRA (Black Canary, Spider-Man Unlimited).