Amidst a fatal diagnosis, Tess Sullivan, a high-powered executive, faces an unimaginable dilemma as her teenage daughter, Pen, plunges into the abyss of self-destruction. At a crossroads, and determined to rescue her daughter, Tess makes a heart-wrenching decision-she will delay her own cancer treatment and embark on an extraordinary journey to save Pen.

As Tess and Pen set off in the scorching sun on the Camino de Santiago pilgrimage across Spain, their departure fills Tess's husband, John, with an overwhelming mix of fear and hope. Aware that their lives hang in the balance, John, in a moment of profound vulnerability, pours his heart into a letter that will alter the course of their lives forever.

While Tess fights to reach her daughter amidst the trials and revelations along the Camino, John's heartfelt letter becomes a guiding light, revealing truths that will test the strength of their family's bond. As Tess's illness takes its toll and Santiago seems more distant than ever, she realizes the gravity of shielding her family from her own grief and pain.

The Grief of Goodbye weaves a tapestry of love, resilience, and the lengths we go to protect those we cherish. Will the unyielding bonds that tie a mother and daughter together be enough to save them?