Evil creatures called Nemeses fall from the skies and the only ones who can fight them are Wizards--infected ones who survived a Nemesis's corruption. Seth, one of these survivors, vows not only to fight the Nemeses, but to find their mythical nest, Radiant, and destroy it!

The battle in Rumble Town rages on, and Konrad shows no signs of stopping the onslaught against his own people. Seth, Mélie and Grimm team up to fight Konrad and the Inquisition, but a new opponent enters the fight--Hameline, a Nemeses Tamer! As the fight rages throughout the city, Rumble Town's entire islet risks collapsing! Will Seth and his friends be able to stop the madness and save everyone in time?